Medicinal product "Zokardis" instructions forapplication is characterized as an effective antihypertensive drug. It is available in the form of tablets covered with a white sheath, slightly convex on both sides. Each of them contains seven and a half milligrams of active ingredient - zofenopril calcium. Auxiliary components are lactose monohydrate, magnesium stearate, microcrystalline cellulose, corn starch and colloidal silicon dioxide.
The shell of the tablets consists of hypromellose, titanium dioxide, macrogol 400 and macrogol 600.
The drug goes on sale in blisters (one or two), placed in cardboard packs. In each blister - seven or fourteen tablets.
The half-life of the drug Zokardis(instruction on how to use this informs) is five and a half hours. It is excreted from the body, mainly by the kidneys (sixty-nine percent), and the intestine (twenty nine percent) also participates in this process.
Zokardis: dosage instructions and recommended dosages
In order to achieve optimal level indicatorsblood pressure, adults are shown to start treatment with fifteen milligrams of the drug (two pills of seven and a half milligrams or half a tablet weighing thirty milligrams) once a day. The dose should be increased gradually (interval - not less than four weeks), the average is thirty milligrams per day, the maximum - sixty.
If a patient has a violationwater-electrolyte balance, then before starting taking Zokardis (the instruction says this), it is necessary to correct the water-electrolyte metabolism, and also to stop using diuretics for at least two days. If it is impossible to comply with the above recommendations, the initial dose of the drug should not be more than seven and a half milligrams.
Patients with impaired renal functionIt is necessary to reduce the standard amount of medicines fourfold. In the normal operation of this body, dose adjustment for the elderly is not required.
Medicinal product "Zokardis" - instruction forapplication informs - take orally without dependence from the use of food. If necessary, you can drink it with a sufficient amount of any liquid.
Overdose of the drug is accompanied bya significant decrease in blood pressure (in extremely rare cases, collapse, myocardial infarction, acute circulatory disturbance of the brain, thromboembolic complications develops), convulsions, stupor.
In case of a significant excess of the recommendeddosage it is necessary to conduct the following medical measures: to transfer the patient to a horizontal position, to introduce a 0.9% solution of sodium chloride, plasma substitutes. In more mild cases, it will be sufficient to wash the stomach.
This medication is contraindicated during pregnancy and breastfeeding.
Against the background of his reception, someside effects: a sharp decrease in blood pressure, chest pain and heart area, orthostatic collapse, myocardial infarction, angina pectoris, arrhythmia, heart palpitations, loss of consciousness. In addition, the following symptoms may appear, indicating a malfunction in the central and peripheral nervous system: dizziness, headaches, weakness, sleep disturbance, depression, anxiety and confusion.
Pharmaceutical means "Zokaridis", reviews of which confirm its effectiveness, can be purchased at pharmacies solely on the prescription of a doctor.